[A12260] CAS 872-50-4 | 1-Methyl-2-pyrrolidinone, 99+%

CAS : 872-50-4
MDL : MFCD00003193
EINECS : 212-828-1

Other name :

N-MethylbutyrolactamN-Methyl-2-pyrrolidone

Chemical Properties

Formula : C5H9NO
Formula weight : 99.13
Melting Point : -24°
Boiling Point : 204°
Flash point : 86°(187°F)
Density : 1.033
Refractive Index : 1.4705
Sensitivity : Hygroscopic. Light Sensitive. Store under Nitrogen. Ambient temperatures.
Form : Liquid
Solubility : Miscible with water, lower alcohols, ketones, ethyl acetate, castor oil, chloroform and benzene. Moderately miscible with aliphatic hydrocarbons.

Literature References

Water-miscible, high-boiling dipolar aprotic solvent, compare N,N-Dimethyl­formamide, A13547 and Dimethyl­ sulfoxide, A13280, used in a wide variety of reactions, e.g.: Nucleophilic displacement reactions with CN-: J. Chem. Soc., 954 (1962). Preparation of thiophenols from unactivated aryl chlorides and Na alkanethiolates: J. Org. Chem., 56, 3728 (1991). Reaction of thiophenol and potassium carbonate in uncatalyzed substitution reactions of chloroanilines and chloroanilides: J. Org. Chem., 56, 862 (1991). Synthesis of alkylaryl and alkylheteroaryl ethers, catalyzed by Cu(I): Tetrahedron, 48, 3633 (1992).

Notes

Light sensitive and hygroscopic. Incompatible with strong oxidizing agents. Hygroscopic.Other References:Beilstein: 106420Merck: 14,6117

Grade Specifications

Grade Specifications

Hazard Statements : H360-H315-H319-H335-H227May damage fertility or the unborn child.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.Combustible liquid.
Precautionary Statements : P210-P305+P351+P338-P302+P352-P321-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.