[A12265] CAS 33100-27-5 | 15-Crown-5, 98% | Alfa
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Brand: Alfa Aesar
33100-27-5 | C10H20O5 | 15-crown-5 ether
Chemical Identifiers
CAS
33100-27-5
Molecular Weight (g/mol)
220.27
Synonym
15-crown-5 ether
SMILES
C1COCCOCCOCCOCCO1
InChI Key
VFTFKUDGYRBSAL-UHFFFAOYSA-N
Molecular Formula
C10H20O5
IUPAC Name
1,4,7,10,13-pentaoxacyclopentadecane
Specifications
Assay (GC)
≥97.5%
Appearance (Color)
Clear colorless to pale yellow
Water Content (Karl Fischer Titration)
≤1%
Identification (FTIR)
Conforms
Refractive Index
1.4640-1.4680 @ 20?C
설명
15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.
15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.
Solubility
Miscible with organic solvents.
Notes
Hygroscopic. Moisture sensitive. Incompatible with strong oxidizing agents and strong acids.
Other References:
Beilstein:1618144
GHS Hazard and Precautionary Statements
Hazard Statements:H302+H332-H315-H319
GHS H StatementH302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements:P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:SB0200000
경고:RUO – Research Use Only
CAS33100-27-5FORMULAC10H20O5EINECS251-379-6MDLMFCD00005110
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
