CAS : 14187-32-7
MDL : MFCD00005098
EINECS : 238-041-3
Chemical Properties
Formula : C20H24O6
Formula weight : 360.41
Melting Point : 160-164°
Boiling Point : 380-384°/679mm
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Sparingly soluble in water.
Literature References
Comparison of the rates of displacement of F- in 1-fluoro-2- or 4-nitrobenzene with KOMe and KO-t-Bu in the presence of this crown ether gave a result (t-BuO- >> MeO-) opposite to the pattern observed in its absence: J. Chem. Soc., Perkin 2, 55 (1973). Promotes the generation of bromochlorocarbene from Chlorodibromomethane, A16938: Syntheis, 783 (1977); Tetrahedron, 33, 363 (1977), and of dibromocarbene from Bromoform, A11904: Org. Synth., 75, 98 (1997). In combination with Benzyltriethylammonium chloride, A13268, promotes the oxidative decarboxylation of arylacetic acids with NaIO4 to give high yields of the aryl aldehydes: Indian J. Chem. B, 35B, 151 (1996). Under the same conditions, phenacyl bromides are converted to benzoic acids. Catalyst for the formation of phenacyl esters from phenacyl bromides and K salts of carboxylic acids in acetonitrile: Synth. Commun., 26, 1747 (1996). Catalyst for the halogenative cleavage of epoxides with Br2 or I2, giving halohydrins in high yields: J. Org. Chem., 63, 1455 (1998). See also 18-Crown-6, A11249 and Appendix 2.
Applications
Dibenzo-18-crown-6, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is an important organic intermediate.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 1162153Merck: 14,2602
| Pakage | 100g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
