[A13234] CAS 421-53-4 | Trifluoroacetaldehyde hydrate, tech., ca 75% in water | Alfa
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Brand: Alfa Aesar
421-53-4 | C2HF3O | trifluoroacetaldehyde
Chemical Identifiers
CAS
421-53-4
Molecular Weight (g/mol)
98.02
MDL Number
MFCD00042444
Synonym
trifluoroacetaldehyde
SMILES
FC(F)(F)C=O
InChI Key
JVTSHOJDBRTPHD-UHFFFAOYSA-N
Molecular Formula
C2HF3O
IUPAC Name
2,2,2-trifluoroacetaldehyde
Specifications
Assay (Aqueous acid-base Titration)
70 – 80%
Refractive Index
1.3375 – 1.3415 @20?C
Form
liquid
Comment
Hydrate reacts with KF reagent as well as free water
Water Content (Karl Fischer Titration)
ca. 41 – 32%
설명
One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4 or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4 or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.
One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4 or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.
Solubility
Soluble in water.
Notes
Store at room temperature. Incompatible with oxidizing agents. Keep in cool place.
Other References:
UN Number:UN1989
GHS Hazard and Precautionary Statements
Hazard Statements:H225-H302-H315-H317-H318-H335
GHS H StatementH225-H318-H302-H317-H335-H315Highly flammable liquid and vapour.Causes serious eye damage.Harmful if swallowed.May cause an allergic skin reaction.May cause respiratory irritation.Causes skin irritation.
Precautionary Statements:P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P272-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P333+P313-P363-P370+P378q-P501c
Risk & Safety
TSCA:YesRTECS Number:KI2850000
경고:RUO – Research Use Only
CAS421-53-4FORMULAC2HF3OHAZARD CLASS3EINECS207-006-4MDLMFCD00042444PACKAGING GROUPII
| Pakage | 10g, 50G |
|---|---|
| brand | Alfa Aesar |
