[A14320] CAS 516-12-1 | N-Iodosuccinimide, 97% | Alfa
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Brand: Alfa Aesar
516-12-1 | C4H4INO2 | N-iodosuccinimide succiniodimide NIS
Chemical Identifiers
CAS
516-12-1
Molecular Weight (g/mol)
224.99
Synonym
N-iodosuccinimide succiniodimide NIS
SMILES
IN1C(=O)CCC1=O
InChI Key
LQZMLBORDGWNPD-UHFFFAOYSA-N
Molecular Formula
C4H4INO2
IUPAC Name
1-iodopyrrolidine-2,5-dione
Specifications
Form
Crystals or powder or crystalline powder.
Comment
Contains a small quantity of dark particulate matter from the manufacturing process.
Identification (FTIR)
Conforms
Appearance (Color)
White to yellow to brown
Assay (Iodometric Titration)
≥96.0 to ≤104.0%%
설명
N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. It is also used to hydrolyze thioglycosides to 1-hydroxyglycosides with triluoroacetic acid. It is involved in the preparation of iodobenzene from 1,6-diynes. Further, it acts as an iodinating agent in chemical synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. It is also used to hydrolyze thioglycosides to 1-hydroxyglycosides with triluoroacetic acid. It is involved in the preparation of iodobenzene from 1,6-diynes. Further, it acts as an iodinating agent in chemical synthesis.
N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. It is also used to hydrolyze thioglycosides to 1-hydroxyglycosides with triluoroacetic acid. It is involved in the preparation of iodobenzene from 1,6-diynes. Further, it acts as an iodinating agent in chemical synthesis.
Solubility
Soluble in dioxane, tetrahydrfuran and acetonitrile. Insoluble in ether and carbon tetrachloride.
Notes
Moisture and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.
Other References:
Beilstein:113917
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H315-H319-H335-H500
Precautionary Statements:P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Risk & Safety
TSCA:NoRTECS Number:WN2817000
경고:RUO – Research Use Only
CAS516-12-1FORMULAC4H4INO2EINECS208-221-6MDLMFCD00005512
| Pakage | 100g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
