CAS : 5457-28-3
UN# : UN3439
MDL : MFCD00022717
Hazard Class : 6.1
EINECS : 000-000-0
Packing Group : III
Other name :
3-Cyanoindole
Chemical Properties
Formula : C9H6N2
Formula weight : 142.16
Melting Point : 177-182°
Sensitivity : Light Sensitive. Ambient temperatures.
Form : Powder
Solubility : Insoluble in water.
Applications
Indole-3-carbonitrile is used as a synthesis reagent for preparation of 4-substituted β-lactams, biologically active indoles, inhibitors of glycogen synthase kinase 3β (GSK-3), indole fragments as inosine monophosphate dehydrogenase (IMPDH) inhibitors and HIV-1 integrase inhibitors. It is also used as a reactant for intramolecular oxidative C-H coupling reactions with Application in medium-ring synthesis techniques and for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H302-H315-H319-H335Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
Other References :
Beilstein : 120888
UN# : UN3439
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
