[A17814] CAS 124-68-5 | 2-Amino-2-methyl-1-propanol, 95%, may cont. ca 5% water

CAS : 124-68-5
MDL : MFCD00008051
EINECS : 204-709-8

Other name :

AMPIsobutanolamine

Chemical Properties

Formula : C4H11NO
Formula weight : 89.14
Melting Point : 24-28°
Boiling Point : 164-166°
Flash point : 67°(152°F)
Density : 0.934
Refractive Index : 1.4455
Sensitivity : Ambient temperatures.
Form : Low melting solid
Solubility : Immiscible with water. Miscible with alcohols.

Literature References

Buffer and phosphate acceptor in assay of phosphatases: Methods of Enzymatic Analysis, 3rd ed., H. U. Bergmeyer, Ed., Verlag Chemie, Weinheim (1984), vol. 4, p76. Precursor of 2-substituted-4,4-dimethyl-2-oxazoline derivatives of carboxylic acids: J. Org. Chem., 39, 2787 (1974), developed by Meyers. The oxazoline, which is readily formed with the acid chloride and thionyl chloride, is stable to base, organometallic reagents, etc., but readily cleaved by dilute acid. For further information on the reactivity of these derivatives, see 2,4,4-Trimethyl-2-oxazoline, L00181. 2-Aryl-4,4-dimethyl-2-oxazolines are activated towards ortho-lithiation: J. Org. Chem., 40, 3058 (1975). Methoxy- or fluoro-substituents in the ortho-position are readily substitutied by organolithiums or Grignards, providing a versatile route to biaryls: J. Am. Chem. Soc ., 97, 7383 (1975). For examples, see: Org. Synth. Coll., 9, 258 (1998). The oxazoline can also be converted to an aldehyde by methylation and borohydride reduction. For reviews of the use of oxazolines in synthesis, see: Angew. Chem. Int. Ed., 15, 270 (1976); Tetrahedron, 41, 837 (1985); 50, 2297 (1994).

Notes

Incompatible withoxidizing agents, strong acids, copper, brass and aluminum.Other References:Beilstein: 505979Merck: 14,449

Grade Specifications

Grade Specifications

Hazard Statements : H315-H319-H227-H402-H412Causes skin irritation.Causes serious eye irritation.Combustible liquid.Harmful to aquatic life.Harmful to aquatic life with long lasting effects.
Precautionary Statements : P280g-P273-P305+P351+P338-P337+P313Wear protective gloves.Avoid release to the environment.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.If eye irritation persists: Get medical advice/attention.