CAS : 996-50-9
UN# : UN2733
MDL : MFCD00009040
Hazard Class : 3
EINECS : 213-637-6
Packing Group : II
Other name :
(Diethylamino)trimethylsilaneTMSDEA
Chemical Properties
Formula : (CH3)3SiN(CH2CH3)2
Formula weight : 145.32
Melting Point : -10°
Boiling Point : 125-126°
Flash point : 10°(50°F)
Density : 0.760
Refractive Index : 1.4110
Sensitivity : Moisture Sensitive. Ambient temperatures.
Form : Liquid
Solubility : Hydrolyzes in water.
Literature References
Moderately powerful silylating agent which functions as its own base (see Appendix 4). In the silylation of alcohols, the reagent is sensitive to steric effects. Thus, the equatorial hydroxyl group of 3-ß-tropanol can be silylated selectively: Acta Chim. Acad. Sci. Hung., 58, 189 (1968); J. Am. Chem. Soc., 96, 5876 (1974). In the presence of MeI, primary amines such as aniline are converted to their N,N-bis(trimethylsilyl) derivatives: J. Organomet. Chem., 510, 1 (1996), and ketones to silyl enol ethers in high yield: Organometallics, 16, 2204 (1997). The combination with an alkyl iodide or bromide also provides a convenient method for generating the iodo- or bromotrialkylsilane equivalent in ring-opening of cyclic ethers. With 1 mol of reagent the main product is the ω-siloxy alkyl halide; excess reagent affords the terminal dihalide: J. Org. Chem., 64, 8024 (1999). Promotes direct 1,4-addition of ɑ-unsubstituted aldehydes to electron deficient olefins, specifically with enones to give δ-keto aldehydes: J. Chem. Soc., Perkin 1, 316 (2001). Alternative conditions were found to be ineffective.
Notes
Moisture Sensitive. Store away from oxidizing agents, water/moisture. Store under inert gas. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.Other References:Beilstein: 635718UN#: UN2733
Grade Specifications
Grade Specifications
Hazard Statements : H225-H314-H318Highly flammable liquid and vapour.Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements : P210-P241-P303+P361+P353-P305+P351+P338-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.Use explosion-proof electrical/ventilating/lighting/ equipment.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
| Pakage | 100g, 25g |
|---|---|
| brand | Alfa Aesar |
