[A18627] CAS 1670-81-1 | Indole-5-carboxylic acid, 98% | Alfa
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Brand: Alfa Aesar
1670-81-1 | C9H6NO2 | 1H-indole-5-carboxylate
Chemical Identifiers
CAS
1670-81-1
Molecular Weight (g/mol)
160.15
Synonym
1H-indole-5-carboxylate
SMILES
[O-]C(=O)C1=CC=C2NC=CC2=C1
InChI Key
IENZCGNHSIMFJE-UHFFFAOYSA-M
Molecular Formula
C9H6NO2
IUPAC Name
1H-indole-5-carboxylate
Specifications
Assay (HPLC)
≥97.5%
Appearance (Color)
White to cream to yellow
Assay (Aqueous acid-base Titration)
≥97.5 to ≤102.5%
Form
Powder
Melting Point (clear melt)
208.0-214.0?C
설명
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
Solubility
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Other References:
Beilstein:124391
GHS Hazard and Precautionary Statements
Hazard Statements:H302+H312-H315-H319-H335
GHS H StatementH315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS1670-81-1FORMULAC9H6NO2EINECS216-799-6MDLMFCD00005678
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
