[B20570] CAS 37052-78-1 | 2-Mercapto-5-methoxybenzimidazole, 99% | Alfa
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Brand: Alfa Aesar
37052-78-1 | C8H8N2OS | 5-methoxy-1,3-dihydro-1,3-benzodiazole-2-thione
Chemical Identifiers
CAS
37052-78-1
Molecular Weight (g/mol)
180.23
MDL Number
MFCD00134581
Synonym
5-methoxy-1,3-dihydro-1,3-benzodiazole-2-thione
SMILES
COC1=CC=C2NC(=S)NC2=C1
InChI Key
KOFBRZWVWJCLGM-UHFFFAOYSA-N
Molecular Formula
C8H8N2OS
IUPAC Name
5-methoxy-2,3-dihydro-1H-1,3-benzodiazole-2-thione
Specifications
Assay (HPLC)
≥98.5%
Form
Powder
Melting Point (clear melt)
255.0-261.0?C
Appearance (Color)
Pale cream to cream
설명
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
Solubility
Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.
Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.
Other References:
Beilstein:3605123
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H317
GHS H StatementH315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P270-P271-P272-P280g-P301+P312-P302+P352-P304+P340-P312-P330-P333+P313-P363-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS37052-78-1FORMULAC8H8N2OSEINECS253-326-2MDLMFCD00134581
| Pakage | 100g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
