[B24567] CAS 1449-46-3 | Benzyltriphenylphosphonium bromide, 98%
0 ₩
1449-46-3 |
CAS : 1449-46-3
MDL : MFCD00031707
EINECS : 215-908-4
Chemical Properties
Formula : C6H5CH2P(C6H5)3Br
Formula weight : 433.34
Melting Point : 293-298°
Sensitivity : Hygroscopic. Ambient temperatures.
Form : Crystalline powder
Solubility : Soluble in water.
Literature References
Wittig reaction of benzylic phosphonium salts with aromatic aldehydes using solid KOH + 18-crown-6 leads to (Z)-stilbenes with good stereoselectivity: Tetrahedron Lett., 37, 4225 (1996). See Appendix 1.
Applications
Benzyltriphenylphosphonium bromide is used as a reactant for stereoselective azidolysis of vinyl epoxides, enantioselective aziridination and Friedel-Crafts cyclization for asymmetric synthesis of dihydrexidine, biomimetic iron(III) mediated oxidative dimerization for synthesis of benzoquinone parvistemin A, enantioselective synthesis of syn-diarylheptanoids from D-glucose, preparation of β-amyloid plaque ligands and decarboxylative cyclopropanation. It react with 4-methyl-oxetan-2-one to produce 4-hydroxy-1-phenyl-1-(triphenyl-l5-phosphanylidene)-pentan-2-one.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H300-H315-H319-H335Fatal if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P280-P305+P351+P338-P309-P310Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.Other References:Beilstein: 3599867
| Pakage | 10g, 250g, 50G |
|---|---|
| brand | Alfa Aesar |
