[H31069] CAS 39687-95-1 | Methyl isocyanoacetate, 95% | Alfa
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Brand: Alfa Aesar
39687-95-1 | C4H7NO2 | methyl 2-(methylideneamino)acetate
Chemical Identifiers
CAS
39687-95-1
Molecular Weight (g/mol)
101.11
Synonym
methyl 2-(methylideneamino)acetate
SMILES
COC(=O)CN=C
InChI Key
ZRGVTTCCASYOFN-UHFFFAOYSA-N
Molecular Formula
C4H7NO2
IUPAC Name
methyl 2-(methylideneamino)acetate
Specifications
Appearance (Color)
Clear pale yellow to dark brown
Form
liquid
Assay (GC)
> 94.0%
Refractive Index
1.4140 – 1.4200 @20?C
설명
Methyl isocyanoacetate is used in the copper-catalyzed, diastereoselective synthesis of oxazolines. It is involved in the direct aldol reaction with carbonyl compounds to prepare corresponding oxazoline by using catechol-copper network catalyst. Further, it is also involved in four-component Ugi condensation reaction. It undergoes asymmetric aldol reaction with fluorinated benzaldehyde using gold(I) as a catalyst.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methyl isocyanoacetate is used in the copper-catalyzed, diastereoselective synthesis of oxazolines. It is involved in the direct aldol reaction with carbonyl compounds to prepare corresponding oxazoline by using catechol-copper network catalyst. Further, it is also involved in four-component Ugi condensation reaction. It undergoes asymmetric aldol reaction with fluorinated benzaldehyde using gold(I) as a catalyst.
Methyl isocyanoacetate is used in the copper-catalyzed, diastereoselective synthesis of oxazolines. It is involved in the direct aldol reaction with carbonyl compounds to prepare corresponding oxazoline by using catechol-copper network catalyst. Further, it is also involved in four-component Ugi condensation reaction. It undergoes asymmetric aldol reaction with fluorinated benzaldehyde using gold(I) as a catalyst.
Solubility
Miscible with organic solvents. Slightly miscible with water.
Notes
Light and moisture sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, hydrated iron(II) sulfate, heavy metals and aluminum. Store in a cool place. Keep the container tightly closed.
Other References:
UN Number:UN2922
GHS Hazard and Precautionary Statements
Hazard Statements:H227-H302+H312+H332-H314
GHS H StatementH331-H314-H318-H227-H302-H312 Toxic if inhaled.Causes severe skin burns and eye damage.Causes serious eye damage.Combustible liquid.Harmful if swallowed.Harmful in contact with skin.
Precautionary Statements:P210-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS39687-95-1FORMULAC4H7NO2HAZARD CLASS8EINECS254-593-8MDLMFCD00000006PACKAGING GROUPII
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
