[H35148] CAS 162537-11-3 | N-Methoxycarbonyl-L-tert-leucine, 98%

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CAS : 162537-11-3
MDL : MFCD07778455

Other name :

N-Moc-L-tert-leucine

Chemical Properties

Formula : C8H15NO4
Formula weight : 189.21
Melting Point : 107-110°
Sensitivity : Keep Cold.
Form : Crystalline powder
Solubility : Soluble in ethyl acetate and methanol.

Applications

The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.

Grade Specifications

GHS Hazard and Precautionary Statements

Precautionary Statements : H315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 36/37/38Irritating to eyes, respiratory system and skin.
안전 문구 : 26-37-60In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste