[H64760] CAS 1535-65-5 | Difluoromethyl phenyl sulfone, 95%

CAS : 1535-65-5
MDL : MFCD01050170

Other name :

(Difluoromethylsulfonyl)benzene

Chemical Properties

Formula : C7H6F2O2S
Formula weight : 192.18
Melting Point : 24-25°
Density : 1.324
Refractive Index : 1.5000
Sensitivity : Store under Nitrogen. Ambient temperatures.
Form : Liquid
Solubility : Soluble in chloroform and water.

Applications

Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements :
Precautionary Statements :

Other References :

Beilstein : 2259218