Open Sidebar
thermofisher_thumnail
Add to Compare Added to Compare

[J60174] CAS 114977-28-5 | Docetaxel, 99% | Alfa

0 ₩

family_key 없음
Brand: Alfa Aesar

114977-28-5 | C43H53NO14 | docetaxel docetaxel, trihydrate docetaxel anhydrous TXL 多西他赛

견적/주문 리스트 추가
  •  Size Guide

    Size Guide

  •  Delivery & Return
    납기
    국내재고 평균 3-5일
    해외재고 평균 3-4주

    견적/주문 요청시 담당자가 확인 후 예상 납기를 안내드립니다

    배송비

    유해화학물, 액체(유리병) : 평균 6,000원(vat별도) ~
    기존화학물, 고체(PE 포장) : 평균 3,000원(vat별도) ~
    견적/주문 요청시 담당자가 확인 후 정확한 배송비를 안내드립니다
  Share
Guaranteed Safe CheckoutTrust
설명

랩파인드 공통 안내

Internal Style Example

Chemical Identifiers

CAS
114977-28-5
Molecular Weight (g/mol)
807.89
Synonym
docetaxel docetaxel, trihydrate docetaxel anhydrous TXL 多西他赛
SMILES
CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
InChI Key
ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Molecular Formula
C43H53NO14
IUPAC Name
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate

Specifications

Assay (HPLC)
99% min.

설명

Docetaxel is a second-generation cytotoxic antimicrotubule agent and is mostly used in the pharmaceutical industry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Docetaxel is an analog of taxol, and is considered to be a cytotoxic, semisynthetic, second-generation taxane that exhibits antineoplastic, antibiotic, and antimicrotubule activities
• Docetaxel is capable of inhibiting cellular mitosis. This compound promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability inhibits the normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions. This results in the persistence of abnormal microtubule structures leading to cell-cycle arrest and cell death

Application

• Docetaxel can inhibit angiogenesis by acting on vascular endothelial growth factor (VEGF) associated with cancer cells
• This compound has been used to investigate the effect of lysosomal autophagic flux in gastric cancer cells

Other References:

Merck Index:14,3397

GHS Hazard and Precautionary Statements

Hazard Statements:H315-H319-H335-H361fd
Precautionary Statements:P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c

Risk & Safety

TSCA:NoRTECS Number:DA4172750

경고:RUO – Research Use Only

CAS114977-28-5FORMULAC43H53NO14MDLMFCD00800737

추가 정보
Pakage

100mg, 1g, 500MG
brand

Alfa Aesar
SKU: J60174 Category:  Brand:
Popular Searches: Sweater Jacket Shirt
My Cart
찜
Recently Viewed
Compare Products (0 Products)
Compare Product
Compare Product
Compare Product
Compare Product
Clear All Let's Compare!
Categories

Send Close
일
시간
분
초
[J60174] CAS 114977-28-5 | Docetaxel, 99% | Alfa

[J60174] CAS 114977-28-5 | Docetaxel, 99% | Alfa

0 ₩

Request a Call Back