[J60814] CAS 1257-08-5 | (-)-Epicatechin gallate | Alfa
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Brand: Alfa Aesar
1257-08-5 | C22H18O10 | epicatechin gallate (-)-epicatechin 3-O-gallate
Chemical Identifiers
CAS
1257-08-5
Molecular Weight (g/mol)
442.38
Synonym
epicatechin gallate (-)-epicatechin 3-O-gallate
SMILES
OC1=CC(O)=C2C[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC2=C1)C1=CC=C(O)C(O)=C1
InChI Key
LSHVYAFMTMFKBA-TZIWHRDSSA-N
Molecular Formula
C22H18O10
IUPAC Name
(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate
Specifications
Appearance (Color)
White to off-white
Form
Powder
Assay from Supplier’s CofA
≥97.0% (HPLC)
설명
(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.
(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.
Solubility
Soluble in water, acetone, DMSO, methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 – 8°C
GHS Hazard and Precautionary Statements
Hazard Statements:
Risk & Safety
TSCA:NoRTECS Number:DH9030000
경고:RUO – Research Use Only
CAS1257-08-5FORMULAC22H18O10MDLMFCD00075936
| Pakage | 10MG, 20mg |
|---|---|
| brand | Alfa Aesar |
