CAS : 54-25-1
MDL : MFCD00006472
EINECS : 200-199-6
Other name :
6-Azauracil riboside2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
Chemical Properties
Formula : C8H11N3O6
Formula weight : 245.19
Melting Point : 160-161°
Sensitivity : Keep Cold.
Form : Powder
Solubility : It is soluble in water.
Applications
6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H301-H311-H332-H351Toxic if swallowed.Toxic in contact with skin.Harmful if inhaled.Suspected of causing cancer.
Precautionary Statements : P261-P301+P310-P361-P302+P352-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.Remove/Take off immediately all contaminated clothing.IF ON SKIN: Wash with plenty of soap and water.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
Other References :
Merck : 14,904
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
