CAS : 73573-88-3
MDL : MFCD05662341
Chemical Properties
Formula : C23H34O5
Formula weight : 390.52
Sensitivity : Keep Cold.
Form : Crystalline solid
Solubility : Soluble in ethanol at 25 mg/mL and in DMSO at 20mg/ml
Applications
Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) , induces apoptosis which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 – 8°COther References : Beilstein: 1269441
Merck : 14,6164
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
위험 문구 :
안전 문구 :
| Pakage | 10MG, 25mg, 5mg |
|---|---|
| brand | Alfa Aesar |
