[J61499] CAS 1405-10-3 | Neomycin sulfate hydrate

CAS : 1405-10-3
MDL : MFCD00150827
EINECS : 215-773-1

Chemical Properties

Formula : C23H46N6O13•3H2SO4•xH2O
Formula weight : 908.87(anhy)
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Soluble in water

Applications

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Other References :
Merck : 14,6454

GHS Hazard and Precautionary Statements

Hazard Statements : H334-H317May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause an allergic skin reaction.
Precautionary Statements : P285-P261-P280-P302+P352-P321-P501aIn case of inadequate ventilation wear respiratory protection.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 42/43May cause sensitization by inhalation and skin contact.
안전 문구 : 22-24-37-45-60Do not breathe dust.Avoid contact with skin.Avoid contact with skin.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste