[J61727] CAS 51-45-6 | Histamine | Alfa
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Brand: Alfa Aesar
51-45-6 | C5H9N3 | 1H-imidazole-5-ethanamine
Chemical Identifiers
CAS
51-45-6
Molecular Weight (g/mol)
111.15
Synonym
1H-imidazole-5-ethanamine
SMILES
NCCC1=CN=CN1
InChI Key
NTYJJOPFIAHURM-UHFFFAOYSA-N
Molecular Formula
C5H9N3
IUPAC Name
2-(1H-imidazol-5-yl)ethan-1-amine
Specifications
Assay from Supplier’s CofA
≥97.0%
Appearance (Color)
White to pale yellow to pale brown
Loss on Drying
≤3.0%
Form
Powder or crystals or crystalline powder
설명
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Solubility
Soluble in water, alcohol, and hot chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Hygroscopic. Handle and store under inert gas. Air sensitive.
Other References:
Merck Index:14,4719UN Number:UN2811Beilstein:2012
GHS Hazard and Precautionary Statements
Hazard Statements:H301-H315-H317-H319-H334-H335
GHS H StatementH301-H334-H315-H319-H317-H335 Toxic if swallowed.May cause allergy or asthma symptoms or breathing difficulties if inhaled.Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P270-P271-P272-P280-P285-P301+P310-P302+P352-P304+P340-P305+P351+P338-P330-P333+P313-P342+P311-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:MS1050000
경고:RUO – Research Use Only
CAS51-45-6FORMULAC5H9N3HAZARD CLASS6.1EINECS200-100-6MDLMFCD00005210,MFCD00128939PACKAGING GROUPIII
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
