[J62168] CAS 17440-83-4 | Amiloride hydrochloride dihydrate
0 ₩
17440-83-4 |
CAS : 17440-83-4
UN# : UN2811
MDL : MFCD00058197
Hazard Class : 6.1
EINECS : 217-958-2
Packing Group : III
Other name :
N-Amidino-3,5-diamino-6-chloropyrazine-2-carboxamide hydrochloride
Chemical Properties
Formula : C6H8ClN7O.HCl•2H2O
Formula weight : 266.09
Melting Point : >240°
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Soluble in water at 50mg/ml
Applications
Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. Amiloride • HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H301Toxic if swallowed.
Precautionary Statements : P264-P270-P301+P310-P321-P405-P501aWash thoroughly after handling.Do not eat, drink or smoke when using this product.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
Other References :
Merck : 14,406
UN# : UN2811
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
