CAS : 56092-81-0
UN# : UN1993
MDL : MFCD06798385
Hazard Class : 3
Packing Group : II
Chemical Properties
Formula : C41H72O9
Formula weight : 709.02
Sensitivity : Store at -20°C.
Form : Solution in ethanol
Solubility : Soluble to 10 mM in Ethanol and to 10 mM in DMSO.
Applications
Ionomycin free acid is a beneficial tool in research to raise intracellular calcium levels. Also this antibiotic can be used to study the calcium transport across the plasma membrane. It has been shown to induce central demyelination , inhibit adrenal bovine TREK-1 channels , and to regulate cell division of mature human B cells . It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochondrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.
Notes
A 10mg/ml solution in ethanolOther References : Beilstein: 3642126
UN# : UN1993
GHS Hazard and Precautionary Statements
Hazard Statements : H301Toxic if swallowed.
Precautionary Statements : P264-P270-P301+P310-P321-P405-P501aWash thoroughly after handling.Do not eat, drink or smoke when using this product.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 11Highly flammable.
안전 문구 : 7/9-16-60Keep container tightly closed and in a well-ventilated place.Keep away from sources of ignition – No smoking.This material and its container must be disposed of as hazardous waste
Pakage | 1mg, 5mg |
---|---|
brand | Alfa Aesar |