[J62452] CAS 73-31-4 | Melatonin, 99+% | Alfa

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Brand: Alfa Aesar

73-31-4 | C13H16N2O2 | melatonin melatol revital melatonin vivitas melovine nature’S harmony MEL pineal hormone rx balance melatonine

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Chemical Identifiers

CAS
73-31-4
Molecular Weight (g/mol)
232.28
Synonym
melatonin melatol revital melatonin vivitas melovine nature’S harmony MEL pineal hormone rx balance melatonine
SMILES
COC1=CC=C2NC=C(CCNC(C)=O)C2=C1
InChI Key
DRLFMBDRBRZALE-UHFFFAOYSA-N
Molecular Formula
C13H16N2O2
IUPAC Name
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide

Specifications

Assay (HPLC)
>99.0%

설명

Melatonin acts as a neurohormone that upregulates antioxidant enzymes and inhibits rat NOS1. It also acts as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Other References:

Merck Index:14,5816Beilstein:205542

GHS Hazard and Precautionary Statements

Hazard Statements:Warning
GHS H StatementH361 Suspected of damaging fertility or the unborn child.
Precautionary Statements:GHS P Statement
P281-P201-P202-P308+P313-P405-P501a
Use personal protective equipment as required.
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Risk & Safety

TSCA:NoRTECS Number:AC5955000

경고:RUO – Research Use Only

CAS73-31-4FORMULAC13H16N2O2EINECS200-797-7MDLMFCD00005655

Pakage

25g, 5g

brand

Alfa Aesar

SKU: J62452 Category:  Brand:
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[J62452] CAS 73-31-4 | Melatonin, 99+% | Alfa

[J62452] CAS 73-31-4 | Melatonin, 99+% | Alfa

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