CAS : 738-70-5
MDL : MFCD00036761
EINECS : 212-006-2
Other name :
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Chemical Properties
Formula : C14H18N4O3
Formula weight : 290.32
Melting Point : 199-203°
Sensitivity : Keep Cold.
Form : Powder
Solubility : Trimethoprim is soluble in water at 0.4 mg/ml. It is also soluble in DMSO at 50 mg/ml and chloroform at 18.2 mg/ml. Soluble in methanol, chloroform, dimethyl sulfoxide, N,N-dimethylacetamide, benzyl alcohol, and propylene glycol. Insoluble in water, diethyl ether and benzene.
Applications
An antibacterial and inhibitor of formylation. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme.Trimethoprim is an antibiotic involved in the treatment of urinary tract infections, middle ear infections and travelerÂ’s diarrhea. It is associated with sulfamethoxazole and interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Furthermore, It is also used to treat and prevent Pneumocystis jiroveci pneumonia.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
Other References :
Beilstein : 625127Merck : 14,9709
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
