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CAS : 94497-51-5
MDL : MFCD00866188
Other name :
AM 80
Chemical Properties
Formula : C22H25NO3
Formula weight : 351.44
Sensitivity : Ambient temperatures.
Form : Solid
Solubility : Soluble to 50 mM in DMSO
Applications
Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 ?M respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo. It has also been shown to suppress the growth of other myeloid and lymphoid malignant cells.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
Other References :
Merck : 14,9047
| Pakage | 10MG, 50mg |
|---|---|
| brand | Alfa Aesar |
