[J64870] CAS 53-85-0 | 5,6-Dichlorobenzimidazole riboside, 98% | Alfa

Brand: Alfa Aesar

53-85-0 | C12H12Cl2N2O4 | (2R,3R,4S,5R)-2-(5,6-dichloro-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

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Chemical Identifiers

CAS
53-85-0
Molecular Weight (g/mol)
319.14
Synonym
(2R,3R,4S,5R)-2-(5,6-dichloro-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=CC(Cl)=C(Cl)C=C12
InChI Key
XHSQDZXAVJRBMX-DDHJBXDOSA-N
Molecular Formula
C12H12Cl2N2O4
IUPAC Name
(2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Specifications

Appearance (Color)
White to pale cream
Form
Powder
Purity
≥97.5% (HPLC)

설명

Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

Solubility
Soluble in DMSO to 75mMSoluble in dimethyl sulfoxide, hot ethanol, dimethyl formamide, (1:2) dimethyl formamide:Phosphate buffer saline, water, methanol and pyridine. Slightly soluble in aqueous buffers.

Notes
Incompatible with heat and oxidizing agents.

Other References:

Beilstein:39123

GHS Hazard and Precautionary Statements

Hazard Statements:

Risk & Safety

TSCA:NoRTECS Number:DD7310000

경고:RUO – Research Use Only

CAS53-85-0FORMULAC12H12Cl2N2O4MDLMFCD00036785

Pakage

100mg, 250mg, 50mg

brand

Alfa Aesar

SKU: J64870 Category:  Brand:
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[J64870] CAS 53-85-0 | 5,6-Dichlorobenzimidazole riboside, 98% | Alfa

[J64870] CAS 53-85-0 | 5,6-Dichlorobenzimidazole riboside, 98% | Alfa

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