[J65076] CAS 5536-17-4 | 9-beta-D-Arabinofuranosyladenine, 99%

CAS : 5536-17-4
MDL : MFCD00065471
EINECS : 226-893-9

Other name :

VidarabineAra-A

Chemical Properties

Formula : C10H13N5O4
Formula weight : 267.24
Sensitivity : Store at -20°C.
Form : Powder
Solubility : Soluble in DMF (10 mg/ml), 0.5 M HCl (50 mg/ml), DMSO (53 mg/ml at 25°C), ethanol (<1 mg/ml at 25°C), and water (3 mg/ml at 25°C).

Applications

Vidarabine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine is an inhibitor of A cyclase and DNA Polymerase. Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling. Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 ?M. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements : H361Suspected of damaging fertility or the unborn child.
Precautionary Statements : P281-P201-P202-P308+P313-P405-P501aUse personal protective equipment as required.Obtain special instructions before use.Do not handle until all safety precautions have been read and understood.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References :

Beilstein : 624881Merck : 14,9976