[J65104] CAS 593-84-0 | Guanidine thiocyanate, Molecular Biology Grade | Alfa
0 ₩
Brand: Alfa Aesar
593-84-0 | C2H6N4S | guanidinium thiocyanate
Chemical Identifiers
CAS
593-84-0
Molecular Weight (g/mol)
118.16
Synonym
guanidinium thiocyanate
SMILES
SC#N.NC(N)=N
InChI Key
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
Molecular Formula
C2H6N4S
IUPAC Name
guanidine; sulfanylformonitrile
Specifications
Appearance (Color)
White to pale yellow
Form
Crystalline powder
Assay from Supplier’s CofA
≥99.0% (TItration)
DNase
None detected
RNase
None detected
설명
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
Solubility
Soluble in water (1420 g/L) at 20°C, and ethanol (5%).
Notes
Light Sensitive. Keep container tightly closed. Store away from oxidizing agents.
Other References:
Beilstein:3563461
GHS Hazard and Precautionary Statements
Hazard Statements:Skin corrosion/irritation (category 1), Hazardous to the aquatic environment (chronic category 3), Acute toxicity (category 4)
Corrosive to the respiratory tract, Causes severe skin burns and eye damage, Contact with acids liberates very toxic gas, Harmful to aquatic life with long lasting effects, Harmful if swallowed, in contact with skin or if inhaled
Risk & Safety
TSCA:YesRTECS Number:XL1225000
경고:RUO – Research Use Only
CAS593-84-0FORMULAC2H6N4SHAZARD CLASS8EINECS209-812-1MDLMFCD00013027PACKAGING GROUPIII
| Pakage | 250g, 50G, 500g |
|---|---|
| brand | Alfa Aesar |
