[J65127] CAS 30516-87-1 | 3′-Azido-3′-deoxythymidine, 98% | Alfa
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Brand: Alfa Aesar
30516-87-1 | C10H13N5O4 | AZT
Chemical Identifiers
CAS
30516-87-1
Molecular Weight (g/mol)
267.25
MDL Number
MFCD00006536
Synonym
zidovudine|Azidothymidine|AZT
SMILES
CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI Key
HBOMLICNUCNMMY-CFQLRCIDNA-N
Molecular Formula
C10H13N5O4
IUPAC Name
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Specifications
Appearance (Color)
White to yellow
Form
Powder
Assay from Supplier’s CofA
≥97.5%
Infrared spectrum
Conforms
설명
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
Solubility
Soluble in water.
Notes
Light Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Other References:
Merck Index:1410123Beilstein:3595791
GHS Hazard and Precautionary Statements
Hazard Statements:Serious eye damage/eye irritation (category 2), Germ cell mutagenicity (category 2), Specific target organ toxicity after single exposure (category 3), Carcinogenicity (category 2), Skin corrosion/irritation (category 2)
Causes serious eye irritation, Suspected of causing genetic defects, May cause respiratory irritation, Suspected of causing cancer, Causes skin irritation
Risk & Safety
TSCA:NoRTECS Number:XP207200
경고:RUO – Research Use Only
CAS30516-87-1FORMULAC10H13N5O4MDLMFCD00006536
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
