[L00355] CAS 128-53-0 | N-Ethylmaleimide, 98+% | Alfa

Brand: Alfa Aesar

128-53-0 | C6H7NO2 | N-ethylmaleimide NEM maleic acid N-ethylimide nem (n ethylmaleimide)

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Chemical Identifiers

CAS
128-53-0
Molecular Weight (g/mol)
125.13
Synonym
N-ethylmaleimide NEM maleic acid N-ethylimide nem (n ethylmaleimide)
SMILES
CCN1C(=O)C=CC1=O
InChI Key
HDFGOPSGAURCEO-UHFFFAOYSA-N
Molecular Formula
C6H7NO2
IUPAC Name
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione

Specifications

Identification (FTIR)
Conforms (UK-sourced material)
Melting Point (clear melt)
40.0-46.0°C
Appearance (Color)
White to cream or pale yellow
Form
Crystals or powder or crystalline powder and/or lumps/chunks or fused solid
Assay (GC)
≥98.0% (UK-sourced material)

설명

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.

Other References:

Merck Index:14,3822UN Number:UN2928Beilstein:112448

GHS Hazard and Precautionary Statements

Hazard Statements:H300-H311-H314-H317-H335
GHS H StatementH300-H311-H314-H318-H317 Fatal if swallowed.Toxic in contact with skin.Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction.
Precautionary Statements:P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c

Risk & Safety

TSCA:YesRTECS Number:UX9625000

경고:RUO – Research Use Only

CAS128-53-0FORMULAC6H7NO2HAZARD CLASS6.1EINECS204-892-4MDLMFCD00005509PACKAGING GROUPII

Pakage

10g, 50G

brand

Alfa Aesar

SKU: L00355 Category:  Brand:
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[L00355] CAS 128-53-0 | N-Ethylmaleimide, 98+% | Alfa

[L00355] CAS 128-53-0 | N-Ethylmaleimide, 98+% | Alfa

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