[L02168] CAS 60-31-1 | Acetylcholine chloride, 98+% | Alfa
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Brand: Alfa Aesar
60-31-1 | C7H16ClNO2 | acetylcholine chloride 氯乙酰胆碱 chloroacetylcholine miochol
Chemical Identifiers
CAS
60-31-1
Molecular Weight (g/mol)
181.66
Synonym
acetylcholine chloride 氯乙酰胆碱 chloroacetylcholine miochol
SMILES
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI Key
JUGOREOARAHOCO-UHFFFAOYSA-M
Molecular Formula
C7H16ClNO2
IUPAC Name
[2-(acetyloxy)ethyl]trimethylazanium chloride
Specifications
Assay (Titration ex Chloride)
≥98.0% to ≤102.0% (dry wt. basis)
Appearance (Color)
White
Loss on Drying
≤1.0 % (105?C, 3 hrs)
Form
Crystals or powder or crystalline powder or fused/lumpy solid
Identification (FTIR)
Conforms
설명
Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Solubility
Soluble in water (600 g/L at 20°C), alcohol, DMSO (36 mg/ml at 25°C), and ethanol (36 mg/ml at 25°C). Insoluble in ether.
Notes
Store away from moisture. Store under dry inert gas. Incompatible with heat,oxidizing agents.
Other References:
Merck Index:14,87Beilstein:3571875
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319-H335
GHS H StatementH315-H319-H335 Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:FZ9800000
경고:RUO – Research Use Only
CAS60-31-1FORMULAC7H16ClNO2EINECS200-468-8MDLMFCD00011698
| Pakage | 100g, 25g |
|---|---|
| brand | Alfa Aesar |
