[L02211] CAS 776-74-9 | Benzhydryl bromide, 90+% | Alfa
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Brand: Alfa Aesar
776-74-9 | C13H11Br | bromodiphenylmethane
Chemical Identifiers
CAS
776-74-9
Molecular Weight (g/mol)
247.14
Synonym
bromodiphenylmethane
SMILES
BrC(C1=CC=CC=C1)C1=CC=CC=C1
InChI Key
OQROAIRCEOBYJA-UHFFFAOYSA-N
Molecular Formula
C13H11Br
IUPAC Name
[bromo(phenyl)methyl]benzene
Specifications
Identification (FTIR)
Conforms
Appearance (Color)
Cream to yellow to orange to red to brown
Assay (GC)
≥90.0%
Form
Crystals or powder or crystalline powder or lumps or fused solid
Melting Point (clear melt)
31.0-44.0?C
설명
Benzhydryl bromide is a halogenated building block. Benzhydryl group was preferred to the commoner benzyl to protect 2-nitrophenol in the Bartoli (vinyl Grignard) synthesis of 7-hydroxyindole. Protection was by reaction with the phenol in the presence of potassium carbonate in acetone; deprotection of the indole was by hydrogenolysis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Benzhydryl bromide is a halogenated building block. Benzhydryl group was preferred to the commoner benzyl to protect 2-nitrophenol in the Bartoli (vinyl Grignard) synthesis of 7-hydroxyindole. Protection was by reaction with the phenol in the presence of potassium carbonate in acetone; deprotection of the indole was by hydrogenolysis.
Benzhydryl bromide is a halogenated building block. Benzhydryl group was preferred to the commoner benzyl to protect 2-nitrophenol in the Bartoli (vinyl Grignard) synthesis of 7-hydroxyindole. Protection was by reaction with the phenol in the presence of potassium carbonate in acetone; deprotection of the indole was by hydrogenolysis.
Solubility
Insoluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents and bases. It is sensitive to moisture. Protect from humidity and water. Store under dry inert gas.
Other References:
UN Number:UN1770Beilstein:638544
GHS Hazard and Precautionary Statements
Hazard Statements:H314-H335
GHS H StatementH314-H318 Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements:P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Risk & Safety
TSCA:YesRTECS Number:PA5350000
경고:RUO – Research Use Only
CAS776-74-9FORMULAC13H11BrHAZARD CLASS8EINECS212-279-8MDLMFCD00000134PACKAGING GROUPII
| Pakage | 100g, 25g, 500g |
|---|---|
| brand | Alfa Aesar |
