[L06374] Trifluoroacetic acid, 99% | Alfa
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Brand: Alfa Aesar
| C2HF3O2 | trifluoressigsaeure
Chemical Identifiers
CAS
76-05-1
Molecular Weight (g/mol)
114.02
MDL Number
MFCD00004169
Synonym
trifluoroacetic acid|acid, trifluoroacetic|acide trifluoroacetique|kyselina trifluoroctova|trifluoressigsaeure
SMILES
OC(=O)C(F)(F)F
InChI Key
DTQVDTLACAAQTR-UHFFFAOYSA-N
Molecular Formula
C2HF3O2
IUPAC Name
trifluoroacetic acid
Specifications
Comment
Material sourced in the U.S. and in other countries
Appearance (Color)
Clear colorless to pale yellow or pale pink
Assay (Aqueous acid-base Titration)
≥98.5 to ≤101.5% (non-U.S. sourced material)
Identification (FTIR)
Conforms (non-U.S. sourced material)
Form
Fuming liquid
설명
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.
Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
Other References:
Merck Index:14,9681UN Number:UN2699Beilstein:742035
GHS Hazard and Precautionary Statements
Hazard Statements:H290-H314-H332-H335
GHS H StatementH314-H332 Causes severe skin burns and eye damage.Harmful if inhaled.
Precautionary Statements:P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c
Risk & Safety
TSCA:YesRTECS Number:AJ9625000
경고:RUO – Research Use Only
CAS76-05-1FORMULAC2HF3O2HAZARD CLASS8EINECS200-929-3MDLMFCD00004169PACKAGING GROUPI
| Pakage | 100ml, 25ml, 500ml |
|---|---|
| brand | Alfa Aesar |
