CAS : 56-92-8
MDL : MFCD00012703
EINECS : 200-298-4
Chemical Properties
Formula : C5H9N3•2HCl
Formula weight : 184.07
Melting Point : 245-249°
Sensitivity : Ambient temperatures.
Solubility : Very soluble in water and methanol. Soluble in ethanol.
Applications
Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents. Store at 4°C.Other References : Beilstein: 3624116
Merck : 14,4719
GHS Hazard and Precautionary Statements
Hazard Statements : H334-H315-H319-H317-H335May cause allergy or asthma symptoms or breathing difficulties if inhaled.Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.May cause respiratory irritation.
Precautionary Statements : P285-P305+P351+P338-P302+P352-P321-P405-P501aIn case of inadequate ventilation wear respiratory protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 36/37/38-42/43Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation and skin contact.
안전 문구 : 22-24-26-37-45-60Do not breathe dust.Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste
| Pakage | 25g, 5g |
|---|---|
| brand | Alfa Aesar |
