[L10619] CAS 7481-89-2 | 2′,3′-Dideoxycytidine, 98+% | Alfa
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Brand: Alfa Aesar
7481-89-2 | C9H13N3O3 | DDC
Chemical Identifiers
CAS
7481-89-2
Molecular Weight (g/mol)
211.22
MDL Number
MFCD00012188
Synonym
zalcitabine|DDC
SMILES
NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1
InChI Key
WREGKURFCTUGRC-KGQMAECUNA-N
Molecular Formula
C9H13N3O3
IUPAC Name
4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
Specifications
Appearance (Color)
White to pale cream
Form
Crystals or crystalline powder or powder
Assay (HPLC)
≥98.0%
Identification (FTIR)
Conforms
설명
2′,3′-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Other References:
Beilstein:654956
GHS Hazard and Precautionary Statements
Hazard Statements:H351
Precautionary Statements:P201-P202-P281-P308+P313-P501c

Risk & Safety
TSCA:NoRTECS Number:HA3870000
경고:RUO – Research Use Only
CAS7481-89-2FORMULAC9H13N3O3MDLMFCD00012188
Pakage | 250mg, 50mg |
---|---|
brand | Alfa Aesar |