CAS : 298-93-1
MDL : MFCD00011964
EINECS : 206-069-5
Other name :
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromideMTT
Chemical Properties
Formula : C18H16BrN5S
Formula weight : 414.33
Melting Point : ca 195° dec.
Sensitivity : Moisture Sensitive. Air Sensitive. Light Sensitive. Store under Nitrogen. Ambient temperatures.
Form : Powder
Solubility : Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.
Applications
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
Other References :
Beilstein : 3825277
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
