[L13392] CAS 2782-91-4 | N,N,N’,N’-Tetramethylthiourea, 98%

CAS : 2782-91-4
MDL : MFCD00008324
EINECS : 220-488-0

Other name :

TMTU

Chemical Properties

Formula : C5H12N2S
Formula weight : 132.23
Melting Point : 75-77°
Boiling Point : 245°
Flash point : 190°(374°F)
Sensitivity : Ambient temperatures.
Form : Crystalline solid

Literature References

Effective poison for halting the Rosenmund reduction of benzoyl chloride at the aldehyde stage: J. Chem. Soc., 2024 (1962). For a review of the Rosenmund reduction, see: Org. React., 4, 362 (1948). See also Palladium, 11722 and Quinoline, A11545. Used in combination with Lawesson’s Reagent, A14530 for converting diesters to bis-thioesters for subsequent radical coupling as a method of ring formation, e.g. in Nicolaou’s syntheses of hemibrevitoxin B and brevitoxin B: J. Am. Chem. Soc., 115, 3558 (1993); 117, 10227 (1995). Ligand for the Pauson-Khand reaction for the synthesis of cyclopentenones (see Octacarbonyl­dicobalt, 13060), mediated by catalytic amounts of cobalt carbonyl: Org. Lett., 7, 593 (2005), or palladium chloride: Synlett, 1657 (2005).

Notes

Other References:Beilstein: 1744916

Grade Specifications

Grade Specifications

Hazard Statements : H302Harmful if swallowed.
Precautionary Statements : P280f-P308+P313-P330-P501aWear protective clothing.IF exposed or concerned: Get medical advice/attention.Rinse mouth.Dispose of contents/container in accordance with local/regional/national/international regulations.