CAS : 2999-46-4
MDL : MFCD00000007
EINECS : 221-077-9
Other name :
Isocyanoacetic acid ethyl ester
Chemical Properties
Formula : CNCH2CO2CH2CH3
Formula weight : 113.12
Boiling Point : 194-196°
Flash point : 84°(183°F)
Density : 1.035
Refractive Index : 1.4220
Sensitivity : Keep Cold. Moisture Sensitive. Light Sensitive.
Solubility : Miscible with organic solvents. Slightly miscible with water.
Literature References
Base-catalyzed Michael addition to nitroalkenes provides a route to substituted pyrroles, valuable as intermediates for porphyrin synthesis: J. Chem. Soc., Chem. Commun., 1098 (1985); Tetrahedron, 46, 7483, 7587 (1990); Org. Synth. Coll., 9, 242 (1998). The method has been extended to nitroaromatics, leading to pyrroles and porphyrins fused with aromatic rings: J. Chem. Soc., Perkin 1, 417 (1996). The terminal carbon also undergoes nucleophilic attack on an acyl chloride to give an ɑ-keto imidoyl chloride, which cyclizes in base to a 2-acyl-5-ethoxy oxazole: Synth. Commun., 26, 1149 (1996).
Notes
Store in cool place. Moisture and light sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.Other References:Beilstein: 3588613
Grade Specifications
Grade Specifications
Hazard Statements : H331-H302-H312-H315-H319-H335-H227Toxic if inhaled.Harmful if swallowed.Harmful in contact with skin.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.Combustible liquid.
Precautionary Statements : P210-P305+P351+P338-P302+P352-P321-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
