CAS : 27784-76-5
MDL : MFCD00075414
EINECS : 000-000-0
Other name :
Diethylphosphonoacetic acid tert butyl ester
Chemical Properties
Formula : C10H21O5P
Formula weight : 252.25
Boiling Point : 100-103°/1.5mm
Flash point : >110°(230°F)
Density : 1.074
Refractive Index : 1.4310
Sensitivity : Ambient temperatures.
Solubility : Not miscible or difficult to mix in water.
Applications
tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,ß-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H315-H319Causes skin irritation.Causes serious eye irritation.
Precautionary Statements : P280-P305+P351+P338-P302+P352-P321-P362-P332+P313Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Take off contaminated clothing and wash before reuse.If skin irritation occurs: Get medical advice/attention.
Other References :
Beilstein : 2050126
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
